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Therapeutic target for prostate cancer


Prostate cancer is a common malignancy among men over the age of 50. The stage at which prostate cancer is diagnosed is critical for determining prognosis as well as choosing appropriate therapies.

Decreased expression of the marker galectin-3 has been reported to correlate with neoplastic progression in prostate cancer; however, increased levels of galectin-3 have been linked to tumorigenicity in a number of other tumor types. In order to reconcile this difference, Wang et al hypothesized that galectin-3 was cleaved during prostate cancer progression. They identified cleaved galectin-3 in later stage prostate cancer, and determined that reducing levels of galectin-3 inhibited the development of metastatic prostate cancer. Thus, cleaved galectin-3 may serve as a diagnostic marker and therapeutic target for prostate cancer progression.

Dr. Raz's group "show[s] that galectin-3 is cleaved during the progression of prostate cancer and might be associated with metastasis, cell growth, and tumorigenicity. … Expression of intact versus cleaved galectin-3 thus might be used as a marker for prognosis of prostate cancer and a therapeutic target for the treatment of prostate cancer."

With more and more people falling prey to the disease of cancer, green tea has arrived with great news for one and all. The link between green tea and prostate cancer prevention is well established now. Earlier whatever claims were being made on green tea and prostate cancer prevention, they were really not very conclusive. There was nothing much that could be confirmed from those studies. However, today things are different. There is information sufficient enough to prove that green tea and prostate cancer prevention go hand in hand.

A recent test was carried on a set of 60 people - half of which were given this medicinal tea and half weren't. After a thorough observation of around 1 year, the results confirmed that while 14 out of the people in the second half (deprived of this tea) were found to develop prostate cancer; the first group had only 1!

The leaves of this plant are processed using a steaming process so that the invincible anti-oxidants present in it are properly retained while preparing this tea. These anti oxidants or Catechins as they are formally called, help in destroying the unwanted cancerous cells. Moreover, they also help in preventing the further growth and development of these self-duplicating cells. Online Pharmacy provides the access to health information and prescription medications.

Thus, they help not only in preventing prostate cancer but other cancer types like breast and liver cancer too. The wonders that this herbal tea can do to your health, is not limited to cancer prevention alone. It is extremely useful in reducing the LDL (bad cholesterol) in the body too. This provides a better protection against the second big health issue - cardiovascular diseases.